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AcaClone pDRAW32 open in new window
Freeware DNA cloning, analysis and visualization software.
(http://www.acaclone.com)

AG BIODV Software open in new window
Links to software developed by the AG BIODV group. Tools for consensus, alignment and definition. Both downloads and executables.
(http://www.gsf.de/biodv/software.html)

AnnHyb - Nucleotidic Sequence Manager open in new window
Free software for working with and managing nucleotide sequences in multiple formats. Many features including sequence annotation, restriction analysis, pattern searching, retrieval from servers. Released under GNU Public Licence.
(http://annhyb.free.fr)

Array Genetics open in new window
Bioinformatics programs, including MendelBase.
(http://www.arraygenetics.com/)

Artemis: A DNA Sequence Viewer and Annotation Tool open in new window
Java program to display a DNA sequence, annotated with features, ORFs. Reads many input formats.
(http://www.sanger.ac.uk/Software/Artemis/)

BSML - Bioinformation Sequence Markup Language open in new window
Extensible language specification and container for bioinformatic data.
(http://www.bsml.org/)

Computer Program for Polyphasic Taxonomy Analysis open in new window
The proBiosys suite of programs compares phenetic, chemotaxonomic and nucleic acid sequence data. Algorithms for polyphasic taxonomy are available to construct Dendrograms, the suite is simple to use.
(http://www.proBiosys.com)

DARWIN open in new window
An interactive tool for peptide and nucleotide sequence analysis
(http://cbrg.inf.ethz.ch/Darwin/index.html)

DNA-Star - Lasergene open in new window
Commercial sequence analysis and manipulation suite for Windows and Macintosh.
(http://www.dnastar.com/)

EMBOSS open in new window
The European Molecular Biology Open Software Suite. An open source project started by the EMBnet community in order to replace proprieatry systems like GCG.
(http://www.uk.embnet.org/Software/EMBOSS/)

GDE for Linux open in new window
An integrated linux environment for bioinformatics and evolutionary analysis based on the Genetic Data Environment (GDE). Contains binaries for Linux and Mac OS X, documentation, screenshots, references, and organism specific interfaces.
(http://www.bioafrica.net/GDElinux/index.html)

Genalysis Genome Analysis Toolkit open in new window
Commercial tool for comparing whole genomes or large genetic sequences. Outputs lists of matches and dot-plots and supports web-based BLAST searches.
(http://www.genpakdna.com/genalysis/index.shtml)

GeneRunner for Windows open in new window
A fairly old sequence analysis tool for everyday lab use. Formerly a commercial product - now "abandonware."
(http://www.generunner.com)

GeneticXchange open in new window
Software for life science discovery; enterprise-level data integration and desktop biologists.
(http://www.geneticxchange.com/)

Gints open in new window
Object-oriented regulation network simulator written in Java. Includes downloadable software and documentation. The site is in French and English.
(http://gints.free.Fr)

HMMER - profile hidden Markov models for sequence analysis open in new window
Sean Eddy's tools to build HMMs from multiple alignments, align sequences to HMMs, calculate e-scores, and other tools
(http://hmmer.wustl.edu/)

Linux Software Encyclopedia - Bioinformatics open in new window
Links to Bioinformatics software for Linux. From the Linux Software Encyclopedia.
(http://stommel.tamu.edu/~baum/linuxlist/linuxlist/node9.html)

Metalifesocieties open in new window
Makes available various bioinformatics algorithms, which perform all essential tasks in sequence analysis and sequence-based predictions.
(http://metalifesocieties.tripod.com/)

Meta-MEME v2.0.1 open in new window
Software toolkit for building and using motif-based hidden Markov models of DNA and proteins - from the Univ. of California-San Diego.
(http://metameme.sdsc.edu/)

Molecular Evolutionary Genetics Analysis (MEGA2) software open in new window
Provides free downloadable MEGA2 software for use in comparative sequence analysis of genetic data. Program for Win32 platforms.
(http://megasoftware.net)

NCBI BLAST open in new window
BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA.
(http://www.ncbi.nlm.nih.gov/BLAST/)

Paracel BLAST open in new window
Software for accelerated parallel BLAST searching
(http://www.paracel.com/products/paracel_blast.html)

PHRED - Base-Calling Software with Quality Information open in new window
A widely-used program for calling DNA sequence bases from sequencer trace files.
(http://www.genome.washington.edu/UWGC/analysistools/Phred.cf)

Phred/Phrap/Consed System Home Page open in new window
basecaller / assembler / sequencer finisher and related tools from the UW Genome Center.
(http://www.phrap.org/)

Premier Biosoft International open in new window
Developers of software for real time PCR primer design, TaqMan, molecular beacons, DNA microarray analysis, drawing restriction plasmid maps, gateway cloning experiments, protein interaction network and functional genomics.
(http://www.PremierBiosoft.com)

PubCrawler - An Update Alerting Service for PubMed and GenBank open in new window
Software and an online service for periodically performing predefined searches at NCBI, reporting new results by email or on the web.
(http://www.pubcrawler.ie)

Public Domain Software in Biology open in new window
The aim of this project is to build the database of public domain software in biology and to distribute these software on-line as well as off-line. These computer software developed by people for people and are available free to potential users. The software collected on this site will be available on-line free for users via internet (e.g. FTP, Email Server, web browser ).
(http://imtech.res.in/pdsb/)

Sequence Analysis for Mac OS X open in new window
A freeware Mac OS X application written in Java that does many standard types of DNA and protein sequence analysis tasks.
(http://www.informagen.com/SA/)

Sight: Extendable parallel system for automatic genome analysis open in new window
Software for analysing all potential genes in a defined genome region. Given two marker names, can output reports of genomic features between them. Features for converting between naming systems, sequence retrieval, E-PCR, gene prediction, similarity search, protein pattern search, and report formatting. Written in Java.
(http://physiologie.uni-ulm.de/kjr/Audrius/Sight/Index.html)

Slcview open in new window
Open source program which allows automated generation of high quality clustergrams and tree images from .cdt files.
(http://slcview.sourceforge.net)

Software for Statistical Folding and Rational Design of Nucleic Acids open in new window
Sfold predicts probable RNA secondary structures, assesses target accessibility, and provides tools for the rational design of RNA-targeting nucleic acids. The web server version is free for academic use.
(http://sfold.wadsworth.org/index.pl)

STRING open in new window
Search for Tandem Repeats IN Genomes -- Includes C source code and examples.
(http://www.caspur.it/~castri/STRING/)

T-Coffee open in new window
T-Coffee is a multiple sequence alignment package using a novel algorithm, available for Unix, MS-DOS, and Mac OS X. Includes binaries, source, references, and documentation.
(http://igs-server.cnrs-mrs.fr/~cnotred/Projects_home_page/t_)

The ARB Project open in new window
A free sequence database application for Unix. It includes a sequence editor, several sequence aligners, phylogeny reconstruction tools, probe/primer search and generation, genome annotation and visualization. In addition to the integrated user-interface the ARB database can be accessed using Perl or C.
(http://www.arb-home.de)

The FASTA package of sequence comparison programs open in new window
William Pearson's package for fast sequence comparison
(ftp://ftp.virginia.edu/pub/fasta)

The Sanger Centre: Software open in new window
Production software used at the Sanger Centre, physical mapping software, informatics and analysis software, and data formats
(http://www.sanger.ac.uk/Software/)

VectorNTI open in new window
Commercial software suite for analysis and manipulation of DNA and protein sequences
(http://www.informaxinc.com/solutions/vectornti/index.html)

Verbumculus Genetic Sequence Analyzer open in new window
An interesting tool to discover and visualize over- or under-represented words in genetic sequences. Executable for Sparc-Solaris, Sparc-Intel or Linux-Intel. Also available as a Java applet.
(http://www.cs.ucr.edu/~stelo/Verbumculus/)

WU-BLAST Archives open in new window
WU-BLAST: The Washington University BLAST. "...faster at any sensitivity, more sensitive at any speed, the first BLAST with gapped alignments and statistics."
(http://blast.wustl.edu/)

www.COMPBIO.net open in new window
Source code and research papers in computational biology. Includes downloadable Visualize molecule visualisation software which supports PDB and DAS files.
(http://www.compbio.net/index.html)

XDigitize open in new window
A visualization software system for evaluation of hybridisation experiments.
(http://www.molgen.mpg.de/~xdigitise/)


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