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Metabolic Pathways
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> Enzyme Kinetics


Citric Acid Cycle open in new window
Diagram of steps in Krebs' tricarboxylic acid cycle, with 3D presentation dependent on Chime plug-in, from student at University of North Texas.
(http://people.unt.edu/~hds0006/tca/index.htm)

Cytochrome P450 Reductase open in new window
Overview of the biology, enzymology, and structure of cytochrome P450 reductase, an unusual electron transfer flavoprotein.
(http://www.uky.edu/Pharmacy/ps/porter/CPR.htm)

DIY Glycolysis by John Maber open in new window
Discusses the conversion of glucose and other monosaccharids to lactate or other biproducts, depending on the organism. Includes an advertisement for the webmaster's book.
(http://www.jonmaber.demon.co.uk/)

EcoCyc Encyclopedia open in new window
Database that describes the genome and the biochemical machinery of E. coli, maintained by SRI International, Menlo Park, CA.
(http://www.ecocyc.org/)

EMP Project , Inc. open in new window
Enzymes and Metabolic Pathways database aiming in 1999 to cover all aspects and be the most comprehensive electronic source of biochemical data from New York.
(http://emp.mcs.anl.gov)

ExPASy - Biochemical Pathways open in new window
Digitized version of wall charts courtesy Boehringer Mannheim et al, divided into Metabolic Pathways and Cellular and Molecular Processes, maintained by the Swiss Institute of Bioinformatics, Geneva, Switzerland.
(http://www.expasy.ch/cgi-bin/search-biochem-index)

General Overview of the Major Metabolic Pathways open in new window
A survey of human metabolism, written for undergraduates in the Health Sciences from a chemist´s point of view. Includes profile of author at University of Oporto, Portugal.
(http://www2.ufp.pt/~pedros/bq/integration.htm)

Glycolysis and the Krebs Cycle open in new window
Chapter from the biology hypertext book at MIT, Cambridge, MA.
(http://web.mit.edu/esgbio/www/glycolysis/dir.html)

Jonathan Dordick Research Group open in new window
Research and publications on biocatalylis, incorportaing polymers to accelerate biological processes. Includes staff profile and contacts at Rensselaer Polytechnic Institute, Troy, NY.
(http://enzymes.che.rpi.edu/)

Kyoto Encyclopedia of Genes and Genomes (KEGG) open in new window
Graphical and hypertext-based information on biochemical pathways, including metabolic and regulatory pathways (for instance, cell cycle and growth factor signaling).
(http://www.genome.ad.jp/kegg/)

Laboratory Research Projects open in new window
Studies on squalene monooxygenase dependent cholesterol biosynthesis, and the role of cytochrome P450 reductase as the electron transfer partner, by Todd D. Porter's group at the College of Pharmacy, Lexington, KY.
(http://www.uky.edu/Pharmacy/ps/porter/)

Metabolic Pathways open in new window
IUBMB-Nicholson chart illustrating glycolytic pathway, Krebs Cycle, and over 500 enzyme reactions, with formulas, substrates, inhibitors and EC numbers. Available as PDF download, or to purchase from Sigma Chemical Co., St.Louis, MO.
(http://www.sigmaaldrich.com/metabolicpathways/)

Metabolic Pathways of Biochemistry open in new window
Graphical representation of metabolic pathways that are crucial to human metabolism, including 3D depictions from the George Washington University, Washington, DC.
(http://www.gwu.edu/~mpb)

Metabolism Foundation open in new window
Non-profit organization dedicated to the study of plant anatomy and physiology, established by Dr. Jim Bidlack, Edmond, OK.
(http://www.metabolism.net/)

MetaCyc - Metabolic Encyclopedia open in new window
Description of over 450 metabolic pathways and their associated enzymes, from over 150 organisms maintained by SRI International, Menlo Park, CA.
(http://biocyc.org/metacyc/)

Molecular Biology Databases - Enzymes and Pathways open in new window
Links to enzyme, metabolic and signaling pathways databases from the Bioinformatics Unit at Weizmann Institute of Science, Israel.
(http://bioinformatics.weizmann.ac.il/mb/db/enzymes.html)

Proteolysis for Fun and Profit open in new window
Protein degradation resource.
(http://www.biochem.emory.edu/protdeg/home.html)

Ubiquitin Index open in new window
The Ubiquitin System for protein modification and degradation.
(http://www.ccc.nottingham.ac.uk/%7Embzmail/students/ub/ubind)

UM-BBD: Biocatalysis/Biodegradation Database open in new window
Microbial enzyme-catalyzed reactions and compounds, FAQ and related resources at the University of Minnesota.
(http://www.labmed.umn.edu/)


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